Herding Effect based Attention for Personalized Time-Sync Video Recommendation

Time-sync comment (TSC) is a new form of user-interaction review associated with real-time video contents, which contains a user's preferences for videos and therefore well suited as the data source for video recommendations. However, existing review-based recommendation methods ignore the context-dependent (generated by user-interaction), real-time, and time-sensitive properties of TSC data. To bridge the above gaps, in this paper, we use video images and users' TSCs to design an Image-Text Fusion model with a novel Herding Effect Attention mechanism (called ITF-HEA), which can predict users' favorite videos with model-based collaborative filtering. Specifically, in the HEA mechanism, we weight the context information based on the semantic similarities and time intervals between each TSC and its context, thereby considering influences of the herding effect in the model. Experiments show that ITF-HEA is on average 3.78\% higher than the state-of-the-art method upon F1-score in baselines.Comment: ACCEPTED for ORAL presentation at IEEE ICME 201

DMCS : Density Modularity based Community Search

Community Search, or finding a connected subgraph (known as a community) containing the given query nodes in a social network, is a fundamental problem. Most of the existing community search models only focus on the internal cohesiveness of a community. However, a high-quality community often has high modularity, which means dense connections inside communities and sparse connections to the nodes outside the community. In this paper, we conduct a pioneer study on searching a community with high modularity. We point out that while modularity has been popularly used in community detection (without query nodes), it has not been adopted for community search, surprisingly, and its application in community search (related to query nodes) brings in new challenges. We address these challenges by designing a new graph modularity function named Density Modularity. To the best of our knowledge, this is the first work on the community search problem using graph modularity. The community search based on the density modularity, termed as DMCS, is to find a community in a social network that contains all the query nodes and has high density-modularity. We prove that the DMCS problem is NP-hard. To efficiently address DMCS, we present new algorithms that run in log-linear time to the graph size. We conduct extensive experimental studies in real-world and synthetic networks, which offer insights into the efficiency and effectiveness of our algorithms. In particular, our algorithm achieves up to 8.5 times higher accuracy in terms of NMI than baseline algorithms

A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis

Current quality control patterns are limited to industrial application, for most the natural chemical reference substances are expensive and unavailable. Here in, quantitative analysis of multi-components with single marker (QAMS) method, is established and validated to simultaneously determine five steroidal saponins (Paris-VII, Paris-H, Paris-II, Dioscin , Paris-I) in Rhizoma Paridis. Using Paris-I as the contrast, the relative correction factors (RCF) of the other four steroidal saponins are determined by HPLC-UV. With in the linear ranges, the values of RCF of Paris-I to Paris-VII, Paris-H, Paris-II and Dioscin are 0.877, 1.087, 0.975 and 1.127, respectively. The RCF has a good reproducibility in various instruments, chromatographic columns (RSD = 0.88 % ~ 4.52 %). According to their RCF, five steroidal saponins are simultaneously determined in Rhizoma Paridis by one marker.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Isolation and identification of compounds present in rhizomes of Paris axialis H. Li and study of their cytotoxic effects

Ten compounds were isolated from the rhizomes of Paris axialis H. Li (PA). Based on spectral data, the isolated compounds were identified as Diosgenin (1), Paris saponin V (2), Paris saponin VI (3), Paris saponin I 4), Paris saponin H (5), Paris saponin II (6), Paris saponin VII (7), luteolin (8), luteoloside (9), isorhamnetin-3-O-α-L-rhamnopyranosyl (1→2)-β-D-glycopyranoside (10). Their cytotoxicity on LA795 cells was evaluated. Paris saponins and flavonoids have synergistic anti-tumor effect on LA795 cells.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Isolation and identification of compounds present in rhizomes of Paris axialis H. Li and study of their cytotoxic effects

Ten compounds were isolated from the rhizomes of Paris axialis H. Li (PA). Based on spectral data, the isolated compounds were identified as Diosgenin (1), Paris saponin V (2), Paris saponin VI (3), Paris saponin I 4), Paris saponin H (5), Paris saponin II (6), Paris saponin VII (7), luteolin (8), luteoloside (9), isorhamnetin-3-O-α-L-rhamnopyranosyl (1→2)-β-D-glycopyranoside (10). Their cytotoxicity on LA795 cells was evaluated. Paris saponins and flavonoids have synergistic anti-tumor effect on LA795 cells.Colegio de Farmacéuticos de la Provincia de Buenos Aire

A quantitative method using one marker for simultaneous assay of steroidal saponins in rhizoma paridis

Current quality control patterns are limited to industrial application, for most the natural chemical reference substances are expensive and unavailable. Here in, quantitative analysis of multi-components with single marker (QAMS) method, is established and validated to simultaneously determine five steroidal saponins (Paris-VII, Paris-H, Paris-II, Dioscin , Paris-I) in Rhizoma Paridis. Using Paris-I as the contrast, the relative correction factors (RCF) of the other four steroidal saponins are determined by HPLC-UV. With in the linear ranges, the values of RCF of Paris-I to Paris-VII, Paris-H, Paris-II and Dioscin are 0.877, 1.087, 0.975 and 1.127, respectively. The RCF has a good reproducibility in various instruments, chromatographic columns (RSD = 0.88 % ~ 4.52 %). According to their RCF, five steroidal saponins are simultaneously determined in Rhizoma Paridis by one marker.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Identification of urinary and feces metabolites of Rhizoma Paridis saponins in rats based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/Q-TOF/MS)

An ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC/QTOF/MS) method was established to analyze the saponins in Rhizoma Paridis saponins (RPS) and the constituents in urinary and feces samples. As we know, the constituents of traditional Chinese medicines are very complex and pre-clinical research including metabolism, excretion and pharmacokinetics of herbal medicine components are of great importance in understanding their biological effects and safety. Therefore, deduction of the metabolic and excretive processes of RPS are necessary. As a result, twenty-two original saponins were detected in RPS-treated urinary and feces. Four excreta were observed in rat feces. Therefore, most original saponins and little deglycosylated saponins have been excreted in the rat urine and feces.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Influence of Croton tiglium seeds on the pharmacokinetics of anthraquinones in Radix et Rhizoma Rhei

In this study, the influence of Croton tiglium seeds on the pharmacokinetic of rhein in Radix et Rhizoma Rhei was performed to elucidate the compatibility relationship of these two herbs. The pharmacokinetics of rhein was studied following oral administration of pure rhein, Radix et Rhizoma Rhei methanol extract (RE) and Radix et Rhizoma Rhei and seeds of Croton tiglium mathanol extract (RCE), with approximately the same dose of 10mg/kg. It was found that comparing with that in monomer, both AUC and Cmax of rhein in RE and different proportion of RCE were significantly different. The results indicated that comparing with the monomer, the concentration of rhein in the plasma was increased in the group of RE whereas the tendency of AUC and Cmax of rhein in RCE presented quite discrepancy depending on the different proportion of RCE.Colegio de Farmacéuticos de la Provincia de Buenos Aire